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Understanding Human Metapneumovirus, as cases emerge from China: Explained

Last week, China’s disease control authority said that it was piloting a monitoring system for pneumonia of unknown origin, with cases of some respiratory diseases expected to rise through the winter. According to a Reuters report, this move to establish a dedicated system was aimed at helping authorities set up protocols to handle unknown pathogens. The country was already witnessing an upward trend in overall infections as of mid-December and was expecting to see more respiratory infections in the winter and spring. One of the pathogens that was detected and which showed an upward trend in the northern provinces, especially among people under the age of 14, was human metapneumovirus, as per the report.

Subsequently, viral posts showcasing crowds of people in what looked like Chinese hospitals began doing the rounds on social media, along with statements about China allegedly declaring an emergency over this virus. However, so far, there has been no such official declaration.

Human metapneumovirus (HMPV) is a virus that usually causes symptoms similar to the common cold. It often causes upper respiratory infections, but it can sometimes cause lower respiratory infections like pneumonia, asthma flare-ups, or make chronic obstructive pulmonary disease (COPD) worse. HMPV infections are more common in the winter and early spring.

Most people get HMPV before they turn 5. You can get HMPV again, but symptoms are usually mild after your first infection.

Is human metapneumovirus just a cold?

Human metapneumovirus most often causes symptoms similar to a cold, but some people can get very sick. You’re more likely to get severely sick the first time you get HMPV, which is why young kids have a greater risk for serious illness. You get some protection (immunity) from your first infection and then are more likely to have mild, cold-like symptoms if you get another HMPV infection. Adults over 65 and people with breathing problems or a weakened immune system may also get severe symptoms.

How common is human metapneumovirus?

Researchers estimate that about 10% to 12% of respiratory illnesses in children are caused by HMPV. Most cases are mild, but about 5% to 16% of children will develop a lower respiratory tract infection like pneumonia.

Is human metapneumovirus the same as RSV?

It’s not the same, but human metapneumovirus is similar to RSV (respiratory syncytial virus). It’s part of the same genus—or scientific grouping—as RSV (pneumovirus) and can cause similar symptoms. The peak age for severe illness from HMPV is between 6 and 12 months, but RSV is more likely to cause severe illness in infants younger than 6 months.

Symptoms and Causes

The symptoms of human metapneumovirus are often similar to the common cold.

What are the symptoms of human metapneumovirus?

Symptoms of human metapneumovirus include:

What causes a human metapneumovirus infection?

A virus—a small germ that uses your cells to make more copies of itself—causes HMPV. It’s part of the same group of viruses that cause RSV, measles, and mumps.

How is human metapneumovirus transmitted?

HMPV spreads through direct contact with someone who has it or from touching things contaminated with the virus. For instance:

What are the risk factors for human metapneumovirus?

Anyone can get HMPV, but you’re at a higher risk for severe illness if you:

What are the complications of human metapneumovirus?

Sometimes HMPV causes complications. These might be serious and require you to be hospitalized. They include:

Diagnosis and Tests

How is human metapneumovirus diagnosed?

Healthcare providers usually diagnose HMPV based on your symptoms and health history. They might use a soft-tipped stick (swab) to get a sample from your nose or throat. A lab tests the sample for viruses and other infections. Keep in mind that you probably won’t be tested for HMPV unless you have serious symptoms.

Sometimes, your provider may also do a bronchoscopy or chest X-rays to look for changes in the airways of your lungs.

Management and Treatment

How is human metapneumovirus treated?

There aren’t any antiviral medications that treat human metapneumovirus. Most people can manage their symptoms at home until they feel better.

If you or your child are severely ill, you might need to be admitted to the hospital. Healthcare providers can monitor your condition and help prevent you from getting sicker. They might treat you with:

Do you need antibiotics for human metapneumovirus?

No. Antibiotics only treat bacteria. Since HMPV is a virus, antibiotics won’t get rid of it. Sometimes people who get pneumonia from HMPV also get a bacterial infection at the same time (secondary infection). If your provider prescribes antibiotics, it would be to treat any secondary infections.

Prevention

Can you prevent a human metapneumovirus infection?

You can reduce your risk of getting HMPV and other infectious diseases by:

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